Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
LMNA P02545 lamin A/C 1.00 0.384 0.885
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
PTCH1 Q13635 patched 1 1.00 0.398 0.885
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
FLNA P21333 filamin A 1.00 0.419 0.846
TWIST1 Q15672 twist family bHLH transcription factor 1 Transcription factor 0.34 0.397 0.846
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.444 0.846
CREBBP Q92793 CREB binding protein 1.00 0.428 0.808
BMP2 P12643 bone morphogenetic protein 2 Signaling 0.99 0.432 0.846
CHD7 Q9P2D1 chromodomain helicase DNA binding protein 7 1.00 0.441 0.846
TBX1 O43435 T-box transcription factor 1 Transcription factor 0.84 0.433 0.808