Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
IL6 | P05231 | interleukin 6 | 0.32 | 0.248 | 0.962 | |
TGFB1 | P01137 | transforming growth factor beta 1 | Signaling | 3.7E-02 | 0.287 | 0.962 |
IFNG | P01579 | interferon gamma | 0.47 | 0.288 | 0.962 | |
BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
ACE | P12821 | angiotensin I converting enzyme | Enzyme | 1.0E-37 | 0.328 | 0.923 |
MMP2 | P08253 | matrix metallopeptidase 2 | Enzyme | 0.84 | 0.333 | 0.923 |
BDNF | P23560 | brain derived neurotrophic factor | Signaling | 0.66 | 0.345 | 0.923 |
LMNA | P02545 | lamin A/C | 1.00 | 0.384 | 0.885 | |
AGT | P01019 | angiotensinogen | Enzyme modulator | 5.0E-08 | 0.367 | 0.923 |
REN | P00797 | renin | Enzyme | 2.4E-07 | 0.370 | 0.923 |
PTPN11 | Q06124 | protein tyrosine phosphatase non-receptor type 11 | 1.00 | 0.385 | 0.923 | |
HRAS | P01112 | HRas proto-oncogene, GTPase | Enzyme modulator | 8.0E-02 | 0.378 | 0.885 |
SIRT1 | Q96EB6 | sirtuin 1 | Epigenetic regulator | 8.7E-02 | 0.378 | 0.885 |
PLG | P00747 | plasminogen | Enzyme | 1.0E-02 | 0.389 | 0.923 |
FLNA | P21333 | filamin A | 1.00 | 0.419 | 0.846 | |
FBN1 | P35555 | fibrillin 1 | Calcium-binding protein | 1.00 | 0.417 | 0.846 |
ELN | P15502 | elastin | 2.1E-14 | 0.415 | 0.885 | |
TGFBR2 | P37173 | transforming growth factor beta receptor 2 | Kinase | 0.13 | 0.413 | 0.846 |
VWF | P04275 | von Willebrand factor | Enzyme modulator | 3.2E-25 | 0.408 | 0.885 |
COL2A1 | P02458 | collagen type II alpha 1 chain | 1.00 | 0.444 | 0.846 | |
F2 | P00734 | coagulation factor II, thrombin | Enzyme | 1.1E-03 | 0.415 | 0.885 |
COL1A1 | P02452 | collagen type I alpha 1 chain | 1.00 | 0.430 | 0.808 | |
MMP3 | P08254 | matrix metallopeptidase 3 | Enzyme | 5.7E-15 | 0.408 | 0.885 |
SMAD3 | P84022 | SMAD family member 3 | Transcription factor | 0.80 | 0.415 | 0.923 |