Disease: Microcephaly
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CRBN Q96SW2 cereblon Enzyme 2.9E-04 0.551 0.654
CREBBP Q92793 CREB binding protein 1.00 0.428 0.808
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
CTSD P07339 cathepsin D Enzyme 9.2E-04 0.478 0.846
CYFIP2 Q96F07 cytoplasmic FMR1 interacting protein 2 Enzyme modulator 1.00 0.633 0.731
DCPS Q96C86 decapping enzyme, scavenger Enzyme 2.5E-07 0.612 0.538
DDB2 Q92466 damage specific DNA binding protein 2 Nucleic acid binding 7.4E-06 0.576 0.654
DDX3X O00571 DEAD-box helicase 3 X-linked 1.00 0.537 0.769
DENND5A Q6IQ26 DENN domain containing 5A 5.8E-02 0.821 0.115
DHCR24 Q15392 24-dehydrocholesterol reductase Enzyme 3.1E-02 0.498 0.769
DHDDS Q86SQ9 dehydrodolichyl diphosphate synthase subunit Enzyme 0.25 0.468 0.885
DLD P09622 dihydrolipoamide dehydrogenase Enzyme 9.5E-03 0.517 0.769
DNM1 Q05193 dynamin 1 Enzyme modulator 1.00 0.595 0.692
DYNC1I2 Q13409 dynein cytoplasmic 1 intermediate chain 2 Cellular structure 1.1E-08 0.760 0.385
EDC3 Q96F86 enhancer of mRNA decapping 3 2.6E-02 0.682 0.308
EEF1A2 Q05639 eukaryotic translation elongation factor 1 alpha 2 Enzyme 1.00 0.554 0.808
ELN P15502 elastin 2.1E-14 0.415 0.885
ENTPD1 P49961 ectonucleoside triphosphate diphosphohydrolase 1 Enzyme 8.1E-03 0.499 0.769
EPRS1 P07814 glutamyl-prolyl-tRNA synthetase 1 Enzyme 1.0E-09 0.644 0.538
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846
ERCC3 P19447 ERCC excision repair 3, TFIIH core complex helicase subunit Enzyme 3.4E-11 0.504 0.846
ERCC4 Q92889 ERCC excision repair 4, endonuclease catalytic subunit Enzyme 1.4E-12 0.468 0.846
ERCC5 P28715 ERCC excision repair 5, endonuclease 2.7E-13 0.499 0.731
ERCC6 P0DP91 Q03468 ERCC excision repair 6, chromatin remodeling factor 5.2E-22 0.507 0.808
EXOSC3 Q9NQT5 exosome component 3 Enzyme 2.4E-04 0.610 0.692