Disease: TNF receptor-associated periodic fever syndrome (TRAPS)
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
CD14 P08571 CD14 molecule 4.9E-05 0.392 0.885
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
CUX1 P39880 Q13948 cut like homeobox 1 Transcription factor 1.00 0.465 0.846
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
HCLS1 P14317 hematopoietic cell-specific Lyn substrate 1 Cellular structure 1.3E-06 0.539 0.846
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL2RB P14784 interleukin 2 receptor subunit beta Receptor 0.29 0.491 0.846
IL6 P05231 interleukin 6 0.32 0.248 0.962
KHSRP Q92945 KH-type splicing regulatory protein Enzyme 1.00 0.526 0.846
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PSIP1 O75475 PC4 and SFRS1 interacting protein 1 Signaling 1.00 0.490 0.846
SIGLEC7 Q9Y286 sialic acid binding Ig like lectin 7 Receptor 2.4E-07 0.535 0.846
TCF3 P15923 transcription factor 3 Transcription factor 2.6E-02 0.476 0.846
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962