Disease: Acute Megakaryocytic Leukemias
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
CSF1R P07333 colony stimulating factor 1 receptor Kinase 0.13 0.448 0.808
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
ERG P11308 ETS transcription factor ERG Transcription factor 0.96 0.453 0.808
ETV6 P41212 ETS variant transcription factor 6 Transcription factor 0.97 0.477 0.731
FANCB Q8NB91 FA complementation group B 1.00 0.468 0.769
FLT3 P36888 fms related receptor tyrosine kinase 3 Kinase 0.61 0.462 0.654
FOXO1 Q12778 forkhead box O1 1.00 0.433 0.846
HOXC5 Q00444 homeobox C5 Transcription factor 5.8E-05 0.682 0.269
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885
MECOM Q03112 MDS1 and EVI1 complex locus 1.00 0.513 0.731
MLLT10 P55197 MLLT10 histone lysine methyltransferase DOT1L cofactor Transcription factor 1.00 0.551 0.462
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923
MYH11 P35749 myosin heavy chain 11 0.77 0.528 0.731
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
NUP98 P52948 nucleoporin 98 and 96 precursor Enzyme 1.00 0.532 0.577
PICALM Q13492 phosphatidylinositol binding clathrin assembly protein Transporter 1.00 0.592 0.538
PML P29590 promyelocytic leukemia 0.21 0.477 0.846
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
RUNX1T1 Q06455 RUNX1 partner transcriptional co-repressor 1 Transcription factor 0.98 0.530 0.808
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962