Disease: Refractive Errors
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APLP2 Q06481 amyloid beta precursor like protein 2 Enzyme modulator 0.38 0.659 0.462
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
DKK1 O94907 dickkopf WNT signaling pathway inhibitor 1 0.17 0.439 0.885
ERG P11308 ETS transcription factor ERG Transcription factor 0.96 0.453 0.808
FZD5 Q13467 frizzled class receptor 5 G-protein coupled receptor 0.98 0.587 0.615
GJD2 Q9UKL4 gap junction protein delta 2 Cell-cell junction 0.20 0.705 0.500
GRIA4 P48058 glutamate ionotropic receptor AMPA type subunit 4 Ion channel 1.8E-02 0.631 0.615
GRM6 O15303 glutamate metabotropic receptor 6 G-protein coupled receptor 4.5E-17 0.700 0.308
HERC2 O95714 HECT and RLD domain containing E3 ubiquitin protein ligase 2 1.00 0.568 0.692
HGF P14210 hepatocyte growth factor Enzyme 1.00 0.374 0.885
KCNQ5 Q9NR82 potassium voltage-gated channel subfamily Q member 5 Ion channel 0.98 0.686 0.500
LAMA2 P24043 laminin subunit alpha 2 Enzyme modulator 2.4E-47 0.553 0.692
LINC00989 long intergenic non-protein coding RNA 989 0.890 0.115
LRP2 P98164 LDL receptor related protein 2 1.00 0.491 0.846
MAP2K1 Q02750 mitogen-activated protein kinase kinase 1 Kinase 0.90 0.439 0.846
MET P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 0.97 0.380 0.846
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MMP3 P08254 matrix metallopeptidase 3 Enzyme 5.7E-15 0.408 0.885
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
MYOC Q99972 myocilin Cellular structure 7.6E-12 0.595 0.500
MYP2 myopia 2 (high grade, autosomal dominant) 0.659 0.308
PAX6 P26367 paired box 6 1.00 0.450 0.769
PHLDA2 Q53GA4 pleckstrin homology like domain family A member 2 0.15 0.636 0.615
PLK3 Q9H4B4 polo like kinase 3 Kinase 1.9E-06 0.644 0.538
PLXNA2 O75051 plexin A2 1.1E-06 0.447 0.808