Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
ALK Q9UM73 ALK receptor tyrosine kinase Kinase 3.2E-06 0.396 0.846
SOX2 P48431 SRY-box transcription factor 2 Transcription factor 0.71 0.405 0.808
PLAU P00749 plasminogen activator, urokinase Enzyme 2.3E-06 0.425 0.923
TYMS P04818 thymidylate synthetase Enzyme 0.72 0.425 0.846
IDH1 O75874 isocitrate dehydrogenase (NADP(+)) 1 2.6E-12 0.424 0.808
IDH2 P48735 isocitrate dehydrogenase (NADP(+)) 2 0.88 0.434 0.808
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808
KLK3 P07288 kallikrein related peptidase 3 Enzyme 4.4E-06 0.443 0.885
DNMT3A Q9Y6K1 DNA methyltransferase 3 alpha 7.4E-39 0.445 0.846
ASXL1 Q8IXJ9 ASXL transcriptional regulator 1 1.3E-14 0.482 0.808
IDO1 P14902 indoleamine 2,3-dioxygenase 1 3.3E-06 0.454 0.846
NBN O60934 nibrin Nucleic acid binding 2.2E-16 0.467 0.808
CXCL9 Q07325 C-X-C motif chemokine ligand 9 Signaling 2.9E-03 0.462 0.808
YWHAZ P63104 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta Chaperone 0.94 0.475 0.846
HOTAIR HOX transcript antisense RNA 0.475 0.769
H2AX P16104 H2A.X variant histone Nucleic acid binding 0.18 0.484 0.808
MIR146B microRNA 146b 0.496 0.769
CLDN4 O14493 claudin 4 Cell-cell junction 7.0E-05 0.514 0.692