Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MRC1 P22897 mannose receptor C-type 1 0.94 0.413 0.846
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
TSC2 P49815 TSC complex subunit 2 Enzyme modulator 1.00 0.439 0.808
NF1 P21359 neurofibromin 1 Enzyme modulator 0.90 0.440 0.885
VHL P40337 von Hippel-Lindau tumor suppressor Enzyme 8.0E-02 0.443 0.846
STK11 Q15831 serine/threonine kinase 11 Kinase 0.99 0.435 0.808
MEN1 O00255 menin 1 1.00 0.444 0.808
SDHD O14521 succinate dehydrogenase complex subunit D Transporter 0.34 0.472 0.885
SMARCA4 P51532 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 Epigenetic regulator 1.00 0.450 0.885
RB1 P06400 RB transcriptional corepressor 1 Nucleic acid binding 1.00 0.444 0.885
SDHB P21912 succinate dehydrogenase complex iron sulfur subunit B Enzyme 2.4E-04 0.474 0.846
DICER1 Q9UPY3 dicer 1, ribonuclease III Enzyme 1.00 0.446 0.846
BAP1 Q92560 BRCA1 associated protein 1 Enzyme 0.99 0.454 0.731
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
MSH6 P52701 mutS homolog 6 Nucleic acid binding 3.7E-05 0.462 0.731
NBN O60934 nibrin Nucleic acid binding 2.2E-16 0.467 0.808
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
PART1 prostate androgen-regulated transcript 1 0.483 0.885
SDHA P31040 succinate dehydrogenase complex flavoprotein subunit A Enzyme 2.6E-10 0.517 0.731
MSH3 P20585 mutS homolog 3 Nucleic acid binding 7.4E-31 0.474 0.769
PMS2 P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 4.5E-27 0.484 0.808
MITF O75030 melanocyte inducing transcription factor 0.98 0.499 0.808
PKM P14618 pyruvate kinase M1/2 Kinase 0.85 0.482 0.808
FH P07954 fumarate hydratase Enzyme 8.8E-02 0.489 0.846