Source: INFERRED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PTCH1 Q13635 patched 1 1.00 0.398 0.885
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
SDHD O14521 succinate dehydrogenase complex subunit D Transporter 0.34 0.472 0.885
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
SMARCB1 Q12824 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 Nucleic acid binding 1.00 0.434 0.846
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
SDHB P21912 succinate dehydrogenase complex iron sulfur subunit B Enzyme 2.4E-04 0.474 0.846
SDHA P31040 succinate dehydrogenase complex flavoprotein subunit A Enzyme 2.6E-10 0.517 0.731
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885
SDHC Q99643 succinate dehydrogenase complex subunit C 2.0E-04 0.517 0.846
FANCC Q00597 FA complementation group C 2.8E-13 0.507 0.808
BRIP1 Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 6.2E-17 0.507 0.731
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
RAD51C O43502 RAD51 paralog C 6.2E-14 0.533 0.692
NF1 P21359 neurofibromin 1 Enzyme modulator 0.90 0.440 0.885
BMPR1A P36894 bone morphogenetic protein receptor type 1A Kinase 0.90 0.522 0.731
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846
VHL P40337 von Hippel-Lindau tumor suppressor Enzyme 8.0E-02 0.443 0.846
TSC2 P49815 TSC complex subunit 2 Enzyme modulator 1.00 0.439 0.808
MITF O75030 melanocyte inducing transcription factor 0.98 0.499 0.808
XRCC2 O43543 X-ray repair cross complementing 2 4.0E-07 0.512 0.731