Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
F2 | P00734 | coagulation factor II, thrombin | Enzyme | 1.1E-03 | 0.415 | 0.885 |
APP | P05067 | amyloid beta precursor protein | Enzyme modulator | 4.7E-02 | 0.422 | 0.846 |
SQSTM1 | Q13501 | sequestosome 1 | 8.6E-04 | 0.428 | 0.885 | |
SNCA | P37840 | synuclein alpha | Transporter | 0.88 | 0.427 | 0.885 |
PRNP | F7VJQ1 P04156 | prion protein | 6.3E-04 | 0.445 | 0.923 | |
BAX | Q07812 | BCL2 associated X, apoptosis regulator | Signaling | 0.32 | 0.417 | 0.885 |
GRN | P28799 | granulin precursor | 7.0E-02 | 0.435 | 0.846 | |
TSC2 | P49815 | TSC complex subunit 2 | Enzyme modulator | 1.00 | 0.439 | 0.808 |
PRKN | O60260 | parkin RBR E3 ubiquitin protein ligase | Enzyme | 6.9E-07 | 0.431 | 0.846 |
CNR1 | P21554 | cannabinoid receptor 1 | G-protein coupled receptor | 0.51 | 0.446 | 0.808 |
PLAT | P00750 | plasminogen activator, tissue type | Enzyme | 5.7E-05 | 0.445 | 0.885 |
VCP | P55072 | valosin containing protein | 1.00 | 0.469 | 0.923 | |
TGFA | P01135 | transforming growth factor alpha | Signaling | 0.72 | 0.432 | 0.885 |
SLC6A3 | Q01959 | solute carrier family 6 member 3 | Transporter | 1.00 | 0.453 | 0.885 |
BECN1 | Q14457 | beclin 1 | Enzyme modulator | 0.94 | 0.432 | 0.846 |
PSEN1 | P49768 | presenilin 1 | Enzyme | 0.97 | 0.469 | 0.846 |
CSF1R | P07333 | colony stimulating factor 1 receptor | Kinase | 0.13 | 0.448 | 0.808 |
PLA2G6 | O60733 | phospholipase A2 group VI | Enzyme modulator | 2.5E-10 | 0.476 | 0.846 |
PPARGC1A | Q9UBK2 | PPARG coactivator 1 alpha | Transcription factor | 1.00 | 0.453 | 0.885 |
HSPA5 | P11021 | heat shock protein family A (Hsp70) member 5 | 0.77 | 0.434 | 0.885 | |
ATXN2 | Q99700 | ataxin 2 | Nucleic acid binding | 0.85 | 0.482 | 0.808 |
TH | P07101 | tyrosine hydroxylase | 1.7E-06 | 0.462 | 0.885 | |
ERBB4 | Q15303 | erb-b2 receptor tyrosine kinase 4 | Kinase | 1.00 | 0.455 | 0.846 |
OGG1 | O15527 | 8-oxoguanine DNA glycosylase | 3.9E-12 | 0.453 | 0.808 | |
CTSB | P07858 | cathepsin B | Enzyme | 5.9E-11 | 0.457 | 0.846 |