Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
DCTN1 Q14203 dynactin subunit 1 Chaperone 8.4E-02 0.597 0.500
ERBB4 Q15303 erb-b2 receptor tyrosine kinase 4 Kinase 1.00 0.455 0.846
FUS P35637 FUS RNA binding protein Nucleic acid binding 1.00 0.470 0.846
GRN P28799 granulin precursor 7.0E-02 0.435 0.846
IFNG P01579 interferon gamma 0.47 0.288 0.962
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885
NOS1 P29475 nitric oxide synthase 1 1.00 0.408 0.885
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
SLC6A3 Q01959 solute carrier family 6 member 3 Transporter 1.00 0.453 0.885
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
TARDBP Q13148 TAR DNA binding protein 0.99 0.493 0.808
TBK1 Q9UHD2 TANK binding kinase 1 Kinase 7.5E-02 0.513 0.846
TH P07101 tyrosine hydroxylase 1.7E-06 0.462 0.885
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962