Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
APP | P05067 | amyloid beta precursor protein | Enzyme modulator | 4.7E-02 | 0.422 | 0.846 |
BAX | Q07812 | BCL2 associated X, apoptosis regulator | Signaling | 0.32 | 0.417 | 0.885 |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
BDNF | P23560 | brain derived neurotrophic factor | Signaling | 0.66 | 0.345 | 0.923 |
C9orf72 | Q96LT7 | C9orf72-SMCR8 complex subunit | 1.1E-06 | 0.496 | 0.769 | |
CASP3 | P42574 | caspase 3 | Enzyme | 0.10 | 0.351 | 0.923 |
CDK5R1 | Q15078 | cyclin dependent kinase 5 regulatory subunit 1 | Enzyme modulator | 0.91 | 0.529 | 0.808 |
CHRNA7 | P36544 Q494W8 | cholinergic receptor nicotinic alpha 7 subunit | Ion channel | 4.2E-04 | 0.532 | 0.654 |
CHRNB2 | P17787 | cholinergic receptor nicotinic beta 2 subunit | Ion channel | 7.3E-04 | 0.617 | 0.308 |
CNTF | P26441 | ciliary neurotrophic factor | 2.3E-05 | 0.561 | 0.615 | |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
EIF2S1 | P05198 | eukaryotic translation initiation factor 2 subunit alpha | Nucleic acid binding | 0.97 | 0.587 | 0.692 |
F2 | P00734 | coagulation factor II, thrombin | Enzyme | 1.1E-03 | 0.415 | 0.885 |
IDUA | P35475 | alpha-L-iduronidase | Enzyme | 3.8E-13 | 0.499 | 0.846 |
IGF1 | P05019 | insulin like growth factor 1 | 0.27 | 0.318 | 0.885 | |
IGF2 | P01344 | insulin like growth factor 2 | 4.4E-02 | 0.390 | 0.885 | |
LEP | P41159 | leptin | 0.46 | 0.349 | 0.846 | |
PPARG | P37231 | peroxisome proliferator activated receptor gamma | Nuclear receptor | 2.9E-02 | 0.358 | 0.885 |
PRNP | F7VJQ1 P04156 | prion protein | 6.3E-04 | 0.445 | 0.923 | |
PSEN1 | P49768 | presenilin 1 | Enzyme | 0.97 | 0.469 | 0.846 |
SOD2 | P04179 | superoxide dismutase 2 | Enzyme | 0.15 | 0.379 | 0.923 |
TBK1 | Q9UHD2 | TANK binding kinase 1 | Kinase | 7.5E-02 | 0.513 | 0.846 |
TNF | P01375 | tumor necrosis factor | Signaling | 0.80 | 0.231 | 0.962 |
TREM2 | Q9NZC2 | triggering receptor expressed on myeloid cells 2 | 3.3E-09 | 0.519 | 0.769 |