Disease: Memory Loss
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CHRNA7 P36544 Q494W8 cholinergic receptor nicotinic alpha 7 subunit Ion channel 4.2E-04 0.532 0.654
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808
CSF1R P07333 colony stimulating factor 1 receptor Kinase 0.13 0.448 0.808
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
CTSB P07858 cathepsin B Enzyme 5.9E-11 0.457 0.846
FUS P35637 FUS RNA binding protein Nucleic acid binding 1.00 0.470 0.846
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885
LEP P41159 leptin 0.46 0.349 0.846
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885
NTF3 P20783 neurotrophin 3 Signaling 0.93 0.519 0.808
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
PTPN5 P54829 protein tyrosine phosphatase non-receptor type 5 1.4E-03 0.666 0.538
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
SLC6A3 Q01959 solute carrier family 6 member 3 Transporter 1.00 0.453 0.885
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
TARDBP Q13148 TAR DNA binding protein 0.99 0.493 0.808
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962