Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CLN9 ceroid-lipofuscinosis, neuronal 9 0.890 0.115
CAPN8 A6NHC0 calpain 8 1.3E-13 0.861 0.192
TPP1 O14773 tripeptidyl peptidase 1 Enzyme 6.3E-07 0.551 0.808
MAPK13 O15264 mitogen-activated protein kinase 13 Kinase 6.7E-11 0.705 0.577
CLN5 O75503 CLN5 intracellular trafficking protein 1.7E-08 0.705 0.269
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
MAS1 P04201 MAS1 proto-oncogene, G protein-coupled receptor G-protein coupled receptor 8.3E-05 0.533 0.769
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
ATP5MC1 P05496 ATP synthase membrane subunit c locus 1 0.43 0.805 0.308
CTSD P07339 cathepsin D Enzyme 9.2E-04 0.478 0.846
PSAP P07602 prosaposin 0.99 0.532 0.846
LGALS1 P09382 galectin 1 Signaling 4.5E-03 0.435 0.846
NCL P19338 nucleolin Nucleic acid binding 1.00 0.509 0.808
TFEB P19484 transcription factor EB 0.90 0.527 0.731
TAC1 P20366 tachykinin precursor 1 0.75 0.424 0.923
CAPN3 P20807 calpain 3 Enzyme 3.6E-19 0.564 0.615
GRN P28799 granulin precursor 7.0E-02 0.435 0.846
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
PPT1 P50897 palmitoyl-protein thioesterase 1 Enzyme 4.9E-05 0.593 0.808
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
CLCN3 P51790 chloride voltage-gated channel 3 Ion channel 1.00 0.621 0.615
CLCN6 P51797 chloride voltage-gated channel 6 Ion channel 6.1E-08 0.769 0.231
PPP5C P53041 protein phosphatase 5 catalytic subunit 1.00 0.644 0.692
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
PKD1 P98161 polycystin 1, transient receptor potential channel interacting 1.00 0.493 0.769