Disease: Inherited neuropathies
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
DNAJB2 P25686 DnaJ heat shock protein family (Hsp40) member B2 5.4E-05 0.743 0.192
EGR2 P11161 early growth response 2 Nucleic acid binding 0.50 0.547 0.769
FIG4 Q92562 FIG4 phosphoinositide 5-phosphatase 2.3E-34 0.551 0.731
GARS1 P41250 glycyl-tRNA synthetase 1 Enzyme 0.31 0.623 0.500
GDAP1 Q8TB36 ganglioside induced differentiation associated protein 1 3.2E-08 0.612 0.538
GJB1 P08034 gap junction protein beta 1 Cell-cell junction 0.85 0.514 0.731
HINT1 P49773 histidine triad nucleotide binding protein 1 Enzyme 1.8E-03 0.619 0.577
HK1 P19367 hexokinase 1 Kinase 0.91 0.542 0.731
KIF1B O60333 kinesin family member 1B Cellular structure 1.00 0.516 0.808
LMNA P02545 lamin A/C 1.00 0.384 0.885
MAD2L1BP Q15013 MAD2L1 binding protein 1.4E-08 0.623 0.577
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846
MPZ P25189 myelin protein zero 0.27 0.503 0.846
MTMR2 Q13614 myotubularin related protein 2 Enzyme 3.0E-07 0.659 0.538
NDRG1 Q92597 N-myc downstream regulated 1 Enzyme 1.1E-02 0.488 0.731
PMP22 Q01453 peripheral myelin protein 22 Cellular structure 0.91 0.471 0.885
PRX Q9BXM0 periaxin 2.1E-14 0.650 0.577
PXMP2 Q9NR77 peroxisomal membrane protein 2 Receptor 9.2E-03 0.743 0.192
RFC1 P35251 replication factor C subunit 1 0.97 0.541 0.808
RNMT O43148 RNA guanine-7 methyltransferase 5.7E-05 0.647 0.500
SACS Q9NZJ4 sacsin molecular chaperone 1.1E-23 0.606 0.654
SBF2 Q86WG5 SET binding factor 2 Enzyme 6.4E-10 0.619 0.577
SH3TC2 Q8TF17 SH3 domain and tetratricopeptide repeats 2 8.3E-16 0.666 0.385
SPG7 Q9UQ90 SPG7 matrix AAA peptidase subunit, paraplegin Enzyme 2.0E-36 0.436 0.885
SPTLC1 O15269 serine palmitoyltransferase long chain base subunit 1 Enzyme 4.2E-11 0.650 0.538