Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
IL17A | Q16552 | interleukin 17A | 4.3E-02 | 0.324 | 0.923 | |
HIF1A | Q16665 | hypoxia inducible factor 1 subunit alpha | Transcription factor | 0.98 | 0.327 | 0.923 |
MMP2 | P08253 | matrix metallopeptidase 2 | Enzyme | 0.84 | 0.333 | 0.923 |
MTHFR | P42898 | methylenetetrahydrofolate reductase | 3.2E-10 | 0.337 | 0.885 | |
ABCB1 | P08183 | ATP binding cassette subfamily B member 1 | Transporter | 1.3E-05 | 0.344 | 0.885 |
PPARG | P37231 | peroxisome proliferator activated receptor gamma | Nuclear receptor | 2.9E-02 | 0.358 | 0.885 |
SERPINE1 | P05121 | serpin family E member 1 | Enzyme modulator | 4.4E-02 | 0.359 | 0.885 |
NOS3 | P29474 | nitric oxide synthase 3 | 6.7E-07 | 0.378 | 0.885 | |
PON1 | P27169 | paraoxonase 1 | 9.8E-11 | 0.409 | 0.885 | |
CREBBP | Q92793 | CREB binding protein | 1.00 | 0.428 | 0.808 | |
F5 | P12259 | coagulation factor V | Enzyme | 5.9E-15 | 0.441 | 0.846 |
KL | Q9UEF7 | klotho | Enzyme | 2.2E-04 | 0.448 | 0.769 |
IL23R | Q5VWK5 | interleukin 23 receptor | Signaling | 5.6E-04 | 0.466 | 0.769 |
ANXA2 | P07355 | annexin A2 | 9.8E-05 | 0.453 | 0.808 | |
TFPI | P10646 | tissue factor pathway inhibitor | Enzyme modulator | 0.25 | 0.486 | 0.808 |
SREBF1 | P36956 | sterol regulatory element binding transcription factor 1 | 1.5E-02 | 0.518 | 0.808 | |
BMP6 | P22004 | bone morphogenetic protein 6 | Signaling | 0.76 | 0.531 | 0.808 |
BACH1 | O14867 | BTB domain and CNC homolog 1 | 0.57 | 0.585 | 0.731 | |
ZFHX3 | Q15911 Q6ZP98 | zinc finger homeobox 3 | 0.45 | 0.621 | 0.654 | |
CYP2C8 | P10632 | cytochrome P450 family 2 subfamily C member 8 | 2.0E-22 | 0.615 | 0.615 | |
GRIK1 | P39086 | glutamate ionotropic receptor kainate type subunit 1 | Ion channel | 1.2E-09 | 0.641 | 0.462 |