Disease: Aortic Valve Stenosis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ADAMTS13 Q76LX8 ADAM metallopeptidase with thrombospondin type 1 motif 13 Enzyme 5.1E-15 0.496 0.769
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
CD14 P08571 CD14 molecule 4.9E-05 0.392 0.885
CRYGC P07315 crystallin gamma C 6.1E-04 0.612 0.577
CRYGEP crystallin gamma E, pseudogene 0.666 0.538
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
IDUA P35475 alpha-L-iduronidase Enzyme 3.8E-13 0.499 0.846
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
IL6 P05231 interleukin 6 0.32 0.248 0.962
IL6R P08887 interleukin 6 receptor Signaling 3.2E-05 0.471 0.846
ITGAM P11215 integrin subunit alpha M 3.3E-11 0.443 0.808
JAG1 P78504 jagged canonical Notch ligand 1 1.00 0.429 0.808
LMNA P02545 lamin A/C 1.00 0.384 0.885
MIR146A microRNA 146a 0.398 0.885
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923
NT5E P21589 5'-nucleotidase ecto Enzyme 2.3E-11 0.436 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PTPRC P08575 protein tyrosine phosphatase receptor type C Enzyme 1.00 0.435 0.808
S100A9 P06702 S100 calcium binding protein A9 Calcium-binding protein 0.48 0.433 0.885