Disease: Advanced breast cancer
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
ARHGAP24 Q8N264 Rho GTPase activating protein 24 3.9E-10 0.456 0.808
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
CD276 Q5ZPR3 CD276 molecule Enzyme modulator 2.5E-09 0.505 0.731
CDK4 P11802 cyclin dependent kinase 4 Kinase 6.3E-02 0.412 0.808
CEACAM3 P40198 CEA cell adhesion molecule 3 1.1E-09 0.494 0.731
CEACAM5 P06731 CEA cell adhesion molecule 5 4.2E-10 0.420 0.846
CEACAM7 Q14002 CEA cell adhesion molecule 7 1.3E-07 0.494 0.769
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
GATA3 P23771 GATA binding protein 3 0.90 0.415 0.846
KRT7 P08729 keratin 7 3.1E-12 0.463 0.808
MIR155 microRNA 155 0.384 0.885
NEU1 Q99519 neuraminidase 1 Enzyme 7.3E-05 0.513 0.769
NEURL1 O76050 neuralized E3 ubiquitin protein ligase 1 Enzyme 1.1E-02 0.556 0.538
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PSG2 P11465 pregnancy specific beta-1-glycoprotein 2 1.4E-30 0.492 0.731
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962