Source: INFERRED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
PRKAR1A P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 1.00 0.401 0.846
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
WT1 P19544 WT1 transcription factor Nucleic acid binding 1.00 0.422 0.808
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846
NOTCH3 Q9UM47 notch receptor 3 0.41 0.435 0.808
RAD51 Q06609 RAD51 recombinase 2.7E-02 0.447 0.846
FLI1 Q01543 Fli-1 proto-oncogene, ETS transcription factor Transcription factor 0.99 0.468 0.692
RTEL1 Q9NZ71 regulator of telomere elongation helicase 1 Enzyme 8.9E-10 0.459 0.808
TINF2 Q9BSI4 TERF1 interacting nuclear factor 2 1.3E-03 0.575 0.731
PDGFRB P09619 platelet derived growth factor receptor beta Kinase 0.90 0.416 0.846
BRIP1 Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 6.2E-17 0.507 0.731
RAD51C O43502 RAD51 paralog C 6.2E-14 0.533 0.692
CLCNKB P51801 chloride voltage-gated channel Kb Ion channel 1.4E-22 0.593 0.692
DKC1 O60832 dyskerin pseudouridine synthase 1 Nucleic acid binding 1.00 0.547 0.769
VHL P40337 von Hippel-Lindau tumor suppressor Enzyme 8.0E-02 0.443 0.846
TSC2 P49815 TSC complex subunit 2 Enzyme modulator 1.00 0.439 0.808
TERC telomerase RNA component 0.471 0.846
MITF O75030 melanocyte inducing transcription factor 0.98 0.499 0.808