Disease: Splenomegaly
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923
ADA P00813 adenosine deaminase Enzyme 2.9E-12 0.440 0.885
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
BCR P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 0.99 0.431 0.885
CALR P27797 calreticulin Calcium-binding protein 0.89 0.413 0.923
CASR P41180 calcium sensing receptor G-protein coupled receptor 4.7E-02 0.410 0.846
CD40LG P29965 CD40 ligand Signaling 0.72 0.414 0.846
COG6 Q9Y2V7 component of oligomeric golgi complex 6 6.4E-16 0.644 0.577
CTC1 Q2NKJ3 CST telomere replication complex component 1 1.6E-11 0.601 0.538
DKC1 O60832 dyskerin pseudouridine synthase 1 Nucleic acid binding 1.00 0.547 0.769
FOXP3 Q9BZS1 forkhead box P3 0.99 0.368 0.846
G6PC3 Q9BUM1 glucose-6-phosphatase catalytic subunit 3 4.7E-06 0.606 0.731
GATA2 P23769 GATA binding protein 2 0.98 0.496 0.654
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808
GLB1 P16278 galactosidase beta 1 Enzyme 7.9E-10 0.448 0.808
GPI P06744 glucose-6-phosphate isomerase Enzyme 2.8E-06 0.491 0.769
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923
IDS P22304 iduronate 2-sulfatase 0.95 0.559 0.769
IL6 P05231 interleukin 6 0.32 0.248 0.962
ITCH Q96J02 itchy E3 ubiquitin protein ligase Enzyme 1.00 0.556 0.769
ITK Q08881 IL2 inducible T cell kinase Kinase 3.1E-08 0.555 0.769
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
LIG4 P49917 DNA ligase 4 4.2E-06 0.478 0.846
LIPA P38571 lipase A, lysosomal acid type Enzyme 5.5E-07 0.564 0.654