Disease: Refractory Cytopenia of Childhood
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923
COL11A2 P13942 collagen type XI alpha 2 chain 0.70 0.435 0.846
MUC1 P15941 mucin 1, cell surface associated 1.9E-02 0.384 0.885
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
RBP1 P09455 retinol binding protein 1 5.9E-06 0.565 0.731
SDHC Q99643 succinate dehydrogenase complex subunit C 2.0E-04 0.517 0.846
TRBV20OR9-2 T cell receptor beta variable 20/OR9-2 (non-functional) 0.403 0.923
NES P48681 nestin 1.6E-06 0.450 0.808
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
EGLN1 Q9GZT9 egl-9 family hypoxia inducible factor 1 0.97 0.540 0.731
EGLN2 Q96KS0 egl-9 family hypoxia inducible factor 2 0.72 0.604 0.731
TICAM2 Q86XR7 Q9Y3B3 toll like receptor adaptor molecule 2 2.6E-03 0.438 0.769
MIR21 microRNA 21 0.363 0.846
MIR210 microRNA 210 0.460 0.846
TMED7-TICAM2 Q86XR7 Q9Y3B3 TMED7-TICAM2 readthrough 2.6E-03 0.438 0.769
RAB4B-EGLN2 RAB4B-EGLN2 readthrough (NMD candidate) 0.641 0.654
FH P07954 fumarate hydratase Enzyme 8.8E-02 0.489 0.846
FOLH1 Q04609 folate hydrolase 1 Enzyme 6.2E-09 0.453 0.885
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
SDHB P21912 succinate dehydrogenase complex iron sulfur subunit B Enzyme 2.4E-04 0.474 0.846
VHL P40337 von Hippel-Lindau tumor suppressor Enzyme 8.0E-02 0.443 0.846
BAP1 Q92560 BRCA1 associated protein 1 Enzyme 0.99 0.454 0.731
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
RASSF1 Q9NS23 Ras association domain family member 1 Enzyme modulator 4.9E-06 0.420 0.808