Disease: Pemphigus Vulgaris
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
CCL17 Q92583 C-C motif chemokine ligand 17 Signaling 1.4E-04 0.518 0.808
CCL18 P55774 C-C motif chemokine ligand 18 Signaling 9.2E-03 0.489 0.846
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
POSTN Q15063 periostin Signaling 1.1E-09 0.428 0.885
MS4A1 P11836 membrane spanning 4-domains A1 Receptor 5.1E-05 0.411 0.846
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
HLA-DQA1 P01909 major histocompatibility complex, class II, DQ alpha 1 Immune response 2.4E-02 0.416 0.846
HLA-DQB1 P01920 major histocompatibility complex, class II, DQ beta 1 Immune response 8.9E-03 0.407 0.885
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923
C3 P01024 complement C3 Enzyme modulator 0.90 0.445 0.885
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
MMP12 P39900 matrix metallopeptidase 12 Enzyme 0.484 0.885
PLG P00747 plasminogen Enzyme 1.0E-02 0.389 0.923
CD163 Q86VB7 CD163 molecule Enzyme 8.3E-04 0.427 0.846
HSP90AA1 P07900 heat shock protein 90 alpha family class A member 1 Chaperone 0.86 0.411 0.923
DST Q03001 dystonin Cellular structure 1.00 0.552 0.846
DSP P15924 desmoplakin Cellular structure 1.00 0.514 0.808
DSG1 Q02413 desmoglein 1 Cell adhesion 0.93 0.606 0.538
DSG3 P32926 desmoglein 3 Cell adhesion 1.5E-20 0.603 0.654