Disease: Congenital Abnormality
Source: BEFREE ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CDX2 Q99626 caudal type homeobox 2 Transcription factor 0.53 0.458 0.769
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
CYP2B6 P20813 cytochrome P450 family 2 subfamily B member 6 1.9E-10 0.428 0.846
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ENG P17813 endoglin 1.00 0.446 0.846
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
F2R P25116 coagulation factor II thrombin receptor G-protein coupled receptor 8.5E-03 0.444 0.846
FNDC3A Q9Y2H6 fibronectin type III domain containing 3A 1.00 0.674 0.577
H3P10 H3 histone pseudogene 10 0.350 0.846
HSP90AA1 P07900 heat shock protein 90 alpha family class A member 1 Chaperone 0.86 0.411 0.923
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
NKX2-5 P52952 NK2 homeobox 5 Transcription factor 0.95 0.533 0.692
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
SLC12A3 P55017 solute carrier family 12 member 3 Transporter 3.0E-32 0.493 0.808
SMAD2 Q15796 SMAD family member 2 Transcription factor 1.00 0.456 0.808
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
SMARCA4 P51532 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 Epigenetic regulator 1.00 0.450 0.885
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
STRADA Q7RTN6 STE20 related adaptor alpha Kinase 4.5E-06 0.711 0.462