Disease: Multiple Endocrine Neoplasia Type 1
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PTH P01270 parathyroid hormone 1.2E-02 0.397 0.846
NTRK1 P04629 neurotrophic receptor tyrosine kinase 1 Kinase 2.0E-06 0.422 0.808
MFAP1 P55081 microfibril associated protein 1 Extracellular structure 0.80 0.431 0.846
MEN1 O00255 menin 1 1.00 0.444 0.808
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
MEG3 maternally expressed 3 0.471 0.846
IFI27 P40305 interferon alpha inducible protein 27 1.1E-02 0.437 0.769
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
HTC2 hypertrichosis 2 (generalized, congenital) 0.392 0.808
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
H3P23 H3 histone pseudogene 23 0.443 0.769
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885
GLP1R P43220 glucagon like peptide 1 receptor G-protein coupled receptor 0.29 0.471 0.846
GCG P01275 glucagon 3.5E-02 0.431 0.885
DCTN6 O00399 dynactin subunit 6 Cellular structure 5.6E-02 0.442 0.769
CDKN2C P42773 cyclin dependent kinase inhibitor 2C 0.40 0.527 0.654
CDKN1B P46527 cyclin dependent kinase inhibitor 1B 0.62 0.409 0.769
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CHGA P10645 chromogranin A 3.0E-02 0.490 0.808
CASP8 Q14790 caspase 8 Enzyme 3.7E-06 0.404 0.923
CA9 Q16790 carbonic anhydrase 9 1.3E-09 0.483 0.731
CIB1 Q99828 calcium and integrin binding 1 3.3E-04 0.458 0.769