Disease: TNF receptor-associated periodic fever syndrome (TRAPS)
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AHSA1 O95433 activator of HSP90 ATPase activity 1 1.00 0.396 0.923
AIMP2 Q13155 aminoacyl tRNA synthetase complex interacting multifunctional protein 2 8.0E-03 0.393 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
CRK P46108 CRK proto-oncogene, adaptor protein 0.96 0.394 0.923
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
CUX1 P39880 Q13948 cut like homeobox 1 Transcription factor 1.00 0.465 0.846
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923
FCGR3A P08637 Fc fragment of IgG receptor IIIa Cell adhesion 3.7E-06 0.432 0.962
FCGR3B O75015 Fc fragment of IgG receptor IIIb Cell adhesion 3.0E-07 0.452 0.962
GRAP2 O75791 GRB2 related adaptor protein 2 1.5E-04 0.394 0.923
HCLS1 P14317 hematopoietic cell-specific Lyn substrate 1 Cellular structure 1.3E-06 0.539 0.846
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL2RB P14784 interleukin 2 receptor subunit beta Receptor 0.29 0.491 0.846
IL6 P05231 interleukin 6 0.32 0.248 0.962
KHSRP Q92945 KH-type splicing regulatory protein Enzyme 1.00 0.526 0.846
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923
MEFV O15553 MEFV innate immuity regulator, pyrin 1.0E-14 0.440 0.885
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962
POLDIP2 Q9Y2S7 DNA polymerase delta interacting protein 2 0.41 0.396 0.923
PSIP1 O75475 PC4 and SFRS1 interacting protein 1 Signaling 1.00 0.490 0.846
RNF19A Q9NV58 ring finger protein 19A, RBR E3 ubiquitin protein ligase Enzyme 2.5E-02 0.397 0.923
ROS1 P08922 ROS proto-oncogene 1, receptor tyrosine kinase Kinase 1.6E-72 0.439 0.885