Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923
CREBBP Q92793 CREB binding protein 1.00 0.428 0.808
XRCC1 P18887 X-ray repair cross complementing 1 6.3E-09 0.421 0.923
RUNX2 Q13950 RUNX family transcription factor 2 Transcription factor 0.95 0.437 0.846
EP300 Q09472 E1A binding protein p300 1.00 0.459 0.846
EIF4E P06730 eukaryotic translation initiation factor 4E Nucleic acid binding 0.94 0.448 0.846
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
CREB1 P16220 cAMP responsive element binding protein 1 1.00 0.463 0.885
TAZ Q16635 tafazzin Enzyme 0.73 0.477 0.808
RECQL4 O94761 RecQ like helicase 4 Enzyme 3.3E-35 0.496 0.808
HDAC8 Q9BY41 histone deacetylase 8 Epigenetic regulator 0.98 0.511 0.885
OPN1LW P04000 opsin 1, long wave sensitive G-protein coupled receptor 0.98 0.497 0.808
PAG1 Q9NWQ8 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 1.8E-02 0.505 0.808
WRN Q14191 WRN RecQ like helicase Enzyme 2.6E-34 0.524 0.808
PDE4A P27815 phosphodiesterase 4A 0.98 0.523 0.846
PDK1 Q15118 pyruvate dehydrogenase kinase 1 Kinase 1.1E-05 0.510 0.808
BLM P54132 BLM RecQ like helicase 1.5E-15 0.535 0.808
PCBP4 P57723 poly(rC) binding protein 4 Enzyme 2.4E-03 0.523 0.808
SLURP1 P55000 secreted LY6/PLAUR domain containing 1 0.26 0.560 0.654