Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
VEGFA | P15692 | vascular endothelial growth factor A | Signaling | 2.4E-05 | 0.266 | 0.923 |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
IGF1 | P05019 | insulin like growth factor 1 | 0.27 | 0.318 | 0.885 | |
ALB | P02768 | albumin | Transporter | 0.64 | 0.317 | 0.962 |
HIF1A | Q16665 | hypoxia inducible factor 1 subunit alpha | Transcription factor | 0.98 | 0.327 | 0.923 |
SMUG1 | Q53HV7 | single-strand-selective monofunctional uracil-DNA glycosylase 1 | 4.5E-04 | 0.322 | 0.923 | |
CCND1 | P24385 | cyclin D1 | Enzyme modulator | 0.89 | 0.344 | 0.923 |
SERPINE1 | P05121 | serpin family E member 1 | Enzyme modulator | 4.4E-02 | 0.359 | 0.885 |
GH1 | P01241 | growth hormone 1 | Signaling | 3.0E-02 | 0.373 | 0.923 |
EDN1 | P05305 | endothelin 1 | Signaling | 0.46 | 0.380 | 0.846 |
EPO | P01588 | erythropoietin | 1.1E-02 | 0.381 | 0.885 | |
JAK2 | O60674 | Janus kinase 2 | Kinase | 0.65 | 0.385 | 0.885 |
FBN1 | P35555 | fibrillin 1 | Calcium-binding protein | 1.00 | 0.417 | 0.846 |
NFKB1 | P19838 | nuclear factor kappa B subunit 1 | Transcription factor | 1.00 | 0.396 | 0.923 |
SST | P61278 | somatostatin | Signaling | 0.34 | 0.399 | 0.885 |
CD40 | P25942 | CD40 molecule | 0.85 | 0.396 | 0.846 | |
MAPK8 | P45983 | mitogen-activated protein kinase 8 | Kinase | 1.00 | 0.397 | 0.885 |
MIF | P14174 | macrophage migration inhibitory factor | 1.2E-02 | 0.412 | 0.885 | |
SETD2 | Q9BYW2 | SET domain containing 2, histone lysine methyltransferase | Epigenetic regulator | 1.00 | 0.424 | 0.846 |
RUNX1 | Q01196 | RUNX family transcription factor 1 | Transcription factor | 0.65 | 0.425 | 0.808 |
G6PD | P11413 | glucose-6-phosphate dehydrogenase | Enzyme | 0.97 | 0.424 | 0.846 |
ABL1 | P00519 | ABL proto-oncogene 1, non-receptor tyrosine kinase | Kinase | 1.00 | 0.432 | 0.923 |
BCR | P11274 | BCR activator of RhoGEF and GTPase | Enzyme modulator | 0.99 | 0.431 | 0.885 |
VHL | P40337 | von Hippel-Lindau tumor suppressor | Enzyme | 8.0E-02 | 0.443 | 0.846 |
ENG | P17813 | endoglin | 1.00 | 0.446 | 0.846 |