| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
|---|---|---|---|---|---|---|
| MLH1 | P40692 | mutL homolog 1 | Nucleic acid binding | 3.4E-05 | 0.399 | 0.808 |
| MSH2 | P43246 | mutS homolog 2 | Nucleic acid binding | 0.90 | 0.406 | 0.808 |
| MSH3 | P20585 | mutS homolog 3 | Nucleic acid binding | 7.4E-31 | 0.474 | 0.769 |
| MUTYH | Q9UIF7 | mutY DNA glycosylase | Enzyme | 1.3E-18 | 0.521 | 0.769 |
| MYC | P01106 | MYC proto-oncogene, bHLH transcription factor | Transcription factor | 1.00 | 0.344 | 0.923 |
| MGMT | P16455 | O-6-methylguanine-DNA methyltransferase | 1.2E-07 | 0.412 | 0.885 | |
| PALB2 | Q86YC2 | partner and localizer of BRCA2 | 3.0E-19 | 0.485 | 0.769 | |
| PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
| PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
| PIK3CB | P42338 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta | Kinase | 1.00 | 0.322 | 0.885 |
| PIK3CD | O00329 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta | Kinase | 1.00 | 0.319 | 0.885 |
| PIK3CG | P48736 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma | Kinase | 1.4E-06 | 0.320 | 0.885 |
| PTGS2 | P35354 | prostaglandin-endoperoxide synthase 2 | Enzyme | 1.00 | 0.314 | 0.962 |
| RASSF1 | Q9NS23 | Ras association domain family member 1 | Enzyme modulator | 4.9E-06 | 0.420 | 0.808 |
| REEP5 | Q00765 | receptor accessory protein 5 | Transporter | 7.0E-04 | 0.633 | 0.615 |
| SMAD4 | Q13485 | SMAD family member 4 | Transcription factor | 1.00 | 0.401 | 0.808 |
| SPEN | Q96T58 | spen family transcriptional repressor | 1.00 | 0.644 | 0.654 | |
| TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |