Disease: Hereditary Nonpolyposis Colorectal Cancer
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
ARSA P15289 arylsulfatase A Enzyme 1.1E-11 0.448 0.923
BLM P54132 BLM RecQ like helicase 1.5E-15 0.535 0.808
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962
CDH1 P12830 cadherin 1 0.15 0.401 0.808
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CEACAM5 P06731 CEA cell adhesion molecule 5 4.2E-10 0.420 0.846
CISD3 P0C7P0 CDGSH iron sulfur domain 3 2.0E-02 0.711 0.577
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
DCC P43146 DCC netrin 1 receptor 0.99 0.471 0.808
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
FAP Q12884 fibroblast activation protein alpha Enzyme 1.9E-28 0.496 0.808
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923
H3P10 H3 histone pseudogene 10 0.350 0.846
HDAC2 Q92769 histone deacetylase 2 Epigenetic regulator 1.00 0.476 0.846
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
MCC P23508 MCC regulator of WNT signaling pathway 4.7E-16 0.568 0.731
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
MGMT P16455 O-6-methylguanine-DNA methyltransferase 1.2E-07 0.412 0.885
MIR31 microRNA 31 0.471 0.769