Disease: 21-hydroxylase deficiency
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AKR1C3 P42330 aldo-keto reductase family 1 member C3 Enzyme 7.6E-24 0.529 0.769
C4A P0C0L4 P0C0L5 complement C4A (Rodgers blood group) Enzyme modulator 1.5E-11 0.563 0.769
C4B P0C0L4 P0C0L5 complement C4B (Chido blood group) Enzyme modulator 0.83 0.603 0.808
C4B_2 P0C0L4 P0C0L5 complement component 4B (Chido blood group), copy 2 0.670 0.731
CASR P41180 calcium sensing receptor G-protein coupled receptor 4.7E-02 0.410 0.846
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
CYP2B6 P20813 cytochrome P450 family 2 subfamily B member 6 1.9E-10 0.428 0.846
CYP2C19 P33261 cytochrome P450 family 2 subfamily C member 19 6.5E-20 0.467 0.846
CYP3A4 P08684 cytochrome P450 family 3 subfamily A member 4 Enzyme 5.8E-11 0.462 0.885
DKK1 O94907 dickkopf WNT signaling pathway inhibitor 1 0.17 0.439 0.885
FPR2 P25090 formyl peptide receptor 2 G-protein coupled receptor 0.40 0.547 0.769
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923
HLA-A P04439 major histocompatibility complex, class I, A 1.3E-03 0.370 0.846
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885
HLA-DOA P06340 major histocompatibility complex, class II, DO alpha Immune response 3.0E-10 0.509 0.808
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885
NR1I2 O75469 nuclear receptor subfamily 1 group I member 2 Nuclear receptor 7.3E-09 0.418 0.846
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
TNFRSF11B O00300 TNF receptor superfamily member 11b 0.16 0.422 0.808
TNFRSF1B P20333 TNF receptor superfamily member 1B 0.50 0.425 0.885
TNFSF11 O14788 TNF superfamily member 11 Signaling 4.9E-03 0.453 0.846
TNXB P22105 tenascin XB 1.9E-02 0.572 0.731
TRIM27 P14373 tripartite motif containing 27 1.00 0.572 0.808