Disease: Spastic Paraplegia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCD1 P33897 ATP binding cassette subfamily D member 1 Transporter 1.00 0.563 0.731
AIFM1 O95831 apoptosis inducing factor mitochondria associated 1 Enzyme 1.00 0.527 0.769
ALDH18A1 P54886 aldehyde dehydrogenase 18 family member A1 Enzyme 8.1E-04 0.551 0.769
ALS2 Q96Q42 alsin Rho guanine nucleotide exchange factor ALS2 8.7E-12 0.647 0.423
AP4B1 Q9Y6B7 adaptor related protein complex 4 subunit beta 1 Transporter 1.3E-09 0.631 0.654
AP4E1 Q9UPM8 adaptor related protein complex 4 subunit epsilon 1 Receptor 2.8E-03 0.656 0.385
AP4M1 O00189 adaptor related protein complex 4 subunit mu 1 Extracellular structure 4.5E-17 0.638 0.500
AP4S1 Q9Y587 adaptor related protein complex 4 subunit sigma 1 Transporter 1.7E-06 0.674 0.385
ARX Q96QS3 aristaless related homeobox 0.91 0.516 0.654
ATL1 Q8WXF7 atlastin GTPase 1 Enzyme modulator 0.98 0.593 0.654
ATP13A2 Q9NQ11 ATPase cation transporting 13A2 9.0E-09 0.566 0.577
B4GALNT1 Q00973 beta-1,4-N-acetyl-galactosaminyltransferase 1 3.9E-05 0.644 0.615
BSCL2 Q96G97 BSCL2 lipid droplet biogenesis associated, seipin 1.1E-09 0.545 0.692
C12orf65 Q9H3J6 chromosome 12 open reading frame 65 Nucleic acid binding 0.21 0.678 0.346
C19orf12 Q9NSK7 chromosome 19 open reading frame 12 0.34 0.641 0.615
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CAPN1 P07384 calpain 1 Enzyme 5.9E-10 0.539 0.808
CCT5 P48643 chaperonin containing TCP1 subunit 5 Chaperone 1.00 0.663 0.462
CPT1C Q8TCG5 carnitine palmitoyltransferase 1C Enzyme 2.2E-09 0.691 0.500
CYP2U1 Q7Z449 cytochrome P450 family 2 subfamily U member 1 1.4E-03 0.722 0.462
CYP7B1 O75881 cytochrome P450 family 7 subfamily B member 1 Enzyme 3.3E-06 0.563 0.692
DDHD1 Q8NEL9 DDHD domain containing 1 Enzyme 0.90 0.716 0.423
DDHD2 O94830 DDHD domain containing 2 Enzyme 1.4E-10 0.695 0.577
DSTYK Q6XUX3 dual serine/threonine and tyrosine protein kinase Kinase 0.51 0.700 0.462
ERLIN2 O94905 ER lipid raft associated 2 6.7E-04 0.647 0.500