Disease: Recurrent fevers
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ADA2 Q9NZK5 adenosine deaminase 2 Enzyme 8.1E-08 0.545 0.846
BCAP31 P51572 B cell receptor associated protein 31 Transporter 0.43 0.579 0.808
CRLF1 O75462 cytokine receptor like factor 1 Signaling 4.0E-05 0.597 0.654
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
CYP11B2 P19099 cytochrome P450 family 11 subfamily B member 2 7.1E-19 0.553 0.615
CYP21A2 P08686 cytochrome P450 family 21 subfamily A member 2 2.6E-04 0.525 0.769
ELANE P08246 elastase, neutrophil expressed Enzyme 1.2E-03 0.447 0.846
ELP1 O95163 elongator complex protein 1 Enzyme modulator 2.1E-21 0.579 0.769
GALC P54803 galactosylceramidase 5.2E-15 0.604 0.615
GCH1 P30793 GTP cyclohydrolase 1 Enzyme 0.90 0.511 0.846
IBA57 Q5T440 iron-sulfur cluster assembly factor IBA57 8.4E-03 0.666 0.423
IL1RN P18510 interleukin 1 receptor antagonist 3.1E-02 0.373 0.923
IL2RG P31785 interleukin 2 receptor subunit gamma Signaling 0.99 0.535 0.769
LIFR P42702 LIF receptor subunit alpha Signaling 1.5E-13 0.523 0.808
LPIN2 Q92539 lipin 2 5.0E-05 0.628 0.615
MEFV O15553 MEFV innate immuity regulator, pyrin 1.0E-14 0.440 0.885
MVK Q03426 mevalonate kinase Kinase 0.17 0.576 0.731
NLRC4 Q9NPP4 NLR family CARD domain containing 4 9.9E-12 0.556 0.769
NLRP12 P59046 NLR family pyrin domain containing 12 3.6E-28 0.569 0.846
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962
NOD2 Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 2.0E-30 0.423 0.923
NTRK1 P04629 neurotrophic receptor tyrosine kinase 1 Kinase 2.0E-06 0.422 0.808
ORAI1 Q96D31 ORAI calcium release-activated calcium modulator 1 Ion channel 1.9E-05 0.520 0.808
PEX6 Q13608 peroxisomal biogenesis factor 6 6.3E-06 0.547 0.731
PMP22 Q01453 peripheral myelin protein 22 Cellular structure 0.91 0.471 0.885