Disease: Thrombophilia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
ALB P02768 albumin Transporter 0.64 0.317 0.962
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
CBS P0DN79 P35520 cystathionine beta-synthase Enzyme 3.1E-05 0.465 0.885
CBSL P0DN79 P35520 cystathionine beta-synthase like 0.540 0.808
COX8A P10176 cytochrome c oxidase subunit 8A Enzyme 0.12 0.400 0.846
CPB2 Q96IY4 carboxypeptidase B2 Enzyme 2.7E-17 0.536 0.846
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
F2 P00734 coagulation factor II, thrombin Enzyme 1.1E-03 0.415 0.885
F5 P12259 coagulation factor V Enzyme 5.9E-15 0.441 0.846
HPSE Q9Y251 heparanase Enzyme 2.3E-14 0.425 0.808
IFNG P01579 interferon gamma 0.47 0.288 0.962
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
LPA P08519 lipoprotein(a) Enzyme 6.6E-89 0.444 0.769
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
PROC P04070 protein C, inactivator of coagulation factors Va and VIIIa Enzyme 1.9E-05 0.504 0.808
SERPINB2 P05120 serpin family B member 2 Enzyme modulator 6.4E-12 0.502 0.808
SERPINC1 P01008 serpin family C member 1 Enzyme modulator 1.00 0.507 0.769
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
VKORC1 Q9BQB6 vitamin K epoxide reductase complex subunit 1 Enzyme 0.16 0.603 0.731