Disease: Complications of Diabetes Mellitus
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808
CASP8 Q14790 caspase 8 Enzyme 3.7E-06 0.404 0.923