Disease: Absence Seizures
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ALDH5A1 P51649 aldehyde dehydrogenase 5 family member A1 Enzyme 3.1E-07 0.619 0.462
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
ARX Q96QS3 aristaless related homeobox 0.91 0.516 0.654
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CASK O14936 calcium/calmodulin dependent serine protein kinase Kinase 1.00 0.538 0.808
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962
CDKL5 O76039 cyclin dependent kinase like 5 Kinase 1.00 0.522 0.692
CHAT P28329 choline O-acetyltransferase Enzyme 5.6E-11 0.520 0.808
CHRNA7 P36544 Q494W8 cholinergic receptor nicotinic alpha 7 subunit Ion channel 4.2E-04 0.532 0.654
CLU P10909 clusterin 7.8E-05 0.426 0.885
CSTB P04080 cystatin B Enzyme modulator 6.6E-03 0.530 0.692
EPM2A O95278 EPM2A glucan phosphatase, laforin 8.7E-06 0.608 0.577
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923
FOXG1 P55316 forkhead box G1 0.94 0.522 0.692
GABBR1 Q9UBS5 gamma-aminobutyric acid type B receptor subunit 1 G-protein coupled receptor 1.00 0.587 0.769
GABRB3 P28472 gamma-aminobutyric acid type A receptor subunit beta3 Ion channel 0.95 0.546 0.615
GABRD O14764 gamma-aminobutyric acid type A receptor subunit delta Ion channel 0.99 0.558 0.692
GDI1 P31150 GDP dissociation inhibitor 1 Enzyme 0.99 0.572 0.654
GLUD1 P00367 glutamate dehydrogenase 1 Enzyme 7.0E-03 0.584 0.731
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IQSEC2 Q5JU85 IQ motif and Sec7 domain ArfGEF 2 1.00 0.573 0.577
KCNA2 P16389 potassium voltage-gated channel subfamily A member 2 Ion channel 0.91 0.612 0.577
LEP P41159 leptin 0.46 0.349 0.846
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923