Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
C4A | P0C0L4 P0C0L5 | complement C4A (Rodgers blood group) | Enzyme modulator | 1.5E-11 | 0.563 | 0.769 |
C4B | P0C0L4 P0C0L5 | complement C4B (Chido blood group) | Enzyme modulator | 0.83 | 0.603 | 0.808 |
C4B_2 | P0C0L4 P0C0L5 | complement component 4B (Chido blood group), copy 2 | 0.670 | 0.731 | ||
CRP | P02741 | C-reactive protein | 3.7E-03 | 0.299 | 0.962 | |
CTLA4 | P16410 | cytotoxic T-lymphocyte associated protein 4 | 0.94 | 0.369 | 0.923 | |
HLA-A | P04439 | major histocompatibility complex, class I, A | 1.3E-03 | 0.370 | 0.846 | |
HLA-B | P01889 | major histocompatibility complex, class I, B | 3.9E-05 | 0.379 | 0.885 | |
HLA-DRB1 | P01911 | major histocompatibility complex, class II, DR beta 1 | Immune response | 1.1E-03 | 0.333 | 0.923 |
IL17A | Q16552 | interleukin 17A | 4.3E-02 | 0.324 | 0.923 | |
IL1B | P01584 | interleukin 1 beta | 0.13 | 0.276 | 0.962 | |
IL23R | Q5VWK5 | interleukin 23 receptor | Signaling | 5.6E-04 | 0.466 | 0.769 |
IL6 | P05231 | interleukin 6 | 0.32 | 0.248 | 0.962 | |
PTPN22 | Q9Y2R2 | protein tyrosine phosphatase non-receptor type 22 | 3.5E-21 | 0.438 | 0.846 | |
RBM45 | Q8IUH3 | RNA binding motif protein 45 | 2.1E-10 | 0.383 | 0.846 | |
TLR2 | O60603 | toll like receptor 2 | 1.0E-06 | 0.361 | 0.923 | |
TLR4 | O00206 | toll like receptor 4 | 4.6E-09 | 0.321 | 0.962 | |
TNF | P01375 | tumor necrosis factor | Signaling | 0.80 | 0.231 | 0.962 |