Disease: Adult Rickets
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ADAMTS2 O95450 ADAM metallopeptidase with thrombospondin type 1 motif 2 Enzyme 0.97 0.579 0.808
ALPL P05186 alkaline phosphatase, biomineralization associated Enzyme 3.6E-04 0.546 0.769
ATP7A Q04656 ATPase copper transporting alpha Transporter 1.00 0.494 0.769
BGLAP P02818 bone gamma-carboxyglutamate protein 4.6E-08 0.462 0.846
CLCN5 P51795 chloride voltage-gated channel 5 Ion channel 0.99 0.593 0.577
CYP24A1 Q07973 cytochrome P450 family 24 subfamily A member 1 Enzyme 3.2E-23 0.518 0.692
CYP27B1 O15528 cytochrome P450 family 27 subfamily B member 1 Enzyme 1.9E-07 0.502 0.769
CYP2R1 Q6VVX0 cytochrome P450 family 2 subfamily R member 1 3.8E-10 0.563 0.731
DMP1 Q13316 dentin matrix acidic phosphoprotein 1 1.5E-07 0.556 0.615
FAM20C Q8IXL6 FAM20C golgi associated secretory pathway kinase 0.31 0.578 0.731
FGF23 Q9GZV9 fibroblast growth factor 23 Signaling 3.1E-02 0.460 0.731
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
LRP2 P98164 LDL receptor related protein 2 1.00 0.491 0.846
OCRL Q01968 OCRL inositol polyphosphate-5-phosphatase Enzyme 1.00 0.553 0.731
PHEX P78562 phosphate regulating endopeptidase homolog X-linked Enzyme 1.00 0.548 0.808
PHGDH O43175 phosphoglycerate dehydrogenase Enzyme 1.3E-04 0.484 0.885
PSAT1 Q9Y617 phosphoserine aminotransferase 1 1.1E-08 0.478 0.846
PTH P01270 parathyroid hormone 1.2E-02 0.397 0.846
RAPGEF5 Q92565 Rap guanine nucleotide exchange factor 5 Enzyme modulator 0.98 0.524 0.769
RNU4ATAC RNA, U4atac small nuclear (U12-dependent splicing) 0.556 0.808
SLC34A3 Q8N130 solute carrier family 34 member 3 Transporter 5.9E-14 0.695 0.308
SLC4A1 P02730 solute carrier family 4 member 1 (Diego blood group) Transporter 0.85 0.522 0.731
VDR P11473 vitamin D receptor Nuclear receptor 1.7E-05 0.352 0.885