Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
LEP P41159 leptin 0.46 0.349 0.846
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769
CXCR4 P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 1.8E-02 0.362 0.923
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
HGF P14210 hepatocyte growth factor Enzyme 1.00 0.374 0.885
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
KRT20 P35900 keratin 20 9.1E-11 0.388 0.846
LGALS3 P17931 galectin 3 Signaling 2.3E-05 0.392 0.846
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
CDH1 P12830 cadherin 1 0.15 0.401 0.808