Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TNF | P01375 | tumor necrosis factor | Signaling | 0.80 | 0.231 | 0.962 |
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
IL6 | P05231 | interleukin 6 | 0.32 | 0.248 | 0.962 | |
IL10 | P22301 | interleukin 10 | 5.9E-03 | 0.281 | 0.923 | |
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
AKT1 | P31749 | AKT serine/threonine kinase 1 | Kinase | 0.98 | 0.311 | 0.962 |
BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
PIK3CD | O00329 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta | Kinase | 1.00 | 0.319 | 0.885 |
ACTB | P60709 | actin beta | Cellular structure | 0.99 | 0.325 | 0.923 |
ESR1 | P03372 | estrogen receptor 1 | Nuclear receptor | 1.00 | 0.324 | 0.962 |
PIK3CG | P48736 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma | Kinase | 1.4E-06 | 0.320 | 0.885 |
PIK3CB | P42338 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta | Kinase | 1.00 | 0.322 | 0.885 |
ACE | P12821 | angiotensin I converting enzyme | Enzyme | 1.0E-37 | 0.328 | 0.923 |
SMUG1 | Q53HV7 | single-strand-selective monofunctional uracil-DNA glycosylase 1 | 4.5E-04 | 0.322 | 0.923 | |
CD274 | Q9NZQ7 | CD274 molecule | Receptor | 1.9E-02 | 0.324 | 0.923 |
AR | P10275 | androgen receptor | Nuclear receptor | 0.99 | 0.351 | 0.846 |
VDR | P11473 | vitamin D receptor | Nuclear receptor | 1.7E-05 | 0.352 | 0.885 |
MYC | P01106 | MYC proto-oncogene, bHLH transcription factor | Transcription factor | 1.00 | 0.344 | 0.923 |
TP63 | Q9H3D4 | tumor protein p63 | Transcription factor | 1.00 | 0.362 | 0.769 |
SERPINE1 | P05121 | serpin family E member 1 | Enzyme modulator | 4.4E-02 | 0.359 | 0.885 |