Disease: Keratoderma, Palmoplantar
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AQP5 P55064 aquaporin 5 Ion channel 5.3E-02 0.552 0.769
CD28 P10747 CD28 molecule 0.36 0.436 0.885
COL17A1 Q9UMD9 collagen type XVII alpha 1 chain 2.3E-27 0.545 0.769
CTC1 Q2NKJ3 CST telomere replication complex component 1 1.6E-11 0.601 0.538
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923
DKC1 O60832 dyskerin pseudouridine synthase 1 Nucleic acid binding 1.00 0.547 0.769
GABPA Q06546 GA binding protein transcription factor subunit alpha Transcription factor 1.00 0.379 0.885
GJB2 P29033 gap junction protein beta 2 Cell-cell junction 6.6E-16 0.441 0.846
GJB6 O95452 gap junction protein beta 6 Cell-cell junction 1.7E-07 0.528 0.808
KRT1 P04264 keratin 1 0.74 0.575 0.654
KRT10 P13645 keratin 10 2.5E-03 0.579 0.692
LAMA3 Q16787 laminin subunit alpha 3 Enzyme modulator 8.8E-46 0.576 0.731
MBTPS2 O43462 membrane bound transcription factor peptidase, site 2 Enzyme 1.00 0.513 0.769
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885
NHP2 Q9NX24 NHP2 ribonucleoprotein Nucleic acid binding 5.0E-02 0.623 0.654
NOP10 Q9NPE3 NOP10 ribonucleoprotein Nucleic acid binding 0.77 0.631 0.654
PARN O95453 poly(A)-specific ribonuclease Nucleic acid binding 3.7E-04 0.575 0.769
PEPD P12955 peptidase D Enzyme 1.5E-14 0.621 0.769
PERP Q96FX8 p53 apoptosis effector related to PMP22 7.9E-02 0.663 0.577
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PKP1 Q13835 plakophilin 1 Cellular structure 5.8E-04 0.659 0.462
RTEL1 Q9NZ71 regulator of telomere elongation helicase 1 Enzyme 8.9E-10 0.459 0.808
TERC telomerase RNA component 0.471 0.846
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846
TINF2 Q9BSI4 TERF1 interacting nuclear factor 2 1.3E-03 0.575 0.731