Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
FGFR1 | P11362 | fibroblast growth factor receptor 1 | Kinase | 1.00 | 0.362 | 0.885 |
SLC2A1 | P11166 | solute carrier family 2 member 1 | Transporter | 0.99 | 0.388 | 0.808 |
SOX2 | P48431 | SRY-box transcription factor 2 | Transcription factor | 0.71 | 0.405 | 0.808 |
KMT2A | Q03164 | lysine methyltransferase 2A | 1.00 | 0.410 | 0.885 | |
MECP2 | P51608 | methyl-CpG binding protein 2 | Epigenetic regulator | 0.89 | 0.414 | 0.846 |
FLT1 | P17948 | fms related receptor tyrosine kinase 1 | Kinase | 1.00 | 0.419 | 0.846 |
SNCA | P37840 | synuclein alpha | Transporter | 0.88 | 0.427 | 0.885 |
PRNP | F7VJQ1 P04156 | prion protein | 6.3E-04 | 0.445 | 0.923 | |
MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | |
NKX2-1 | P43699 | NK2 homeobox 1 | Transcription factor | 0.36 | 0.457 | 0.808 |
EHMT1 | Q9H9B1 | euchromatic histone lysine methyltransferase 1 | Epigenetic regulator | 1.00 | 0.460 | 0.808 |
EZR | P15311 | ezrin | Cellular structure | 0.18 | 0.476 | 0.808 |
ATXN2 | Q99700 | ataxin 2 | Nucleic acid binding | 0.85 | 0.482 | 0.808 |
HDAC4 | P56524 | histone deacetylase 4 | Epigenetic regulator | 1.00 | 0.484 | 0.885 |
TSHR | P16473 | thyroid stimulating hormone receptor | G-protein coupled receptor | 3.0E-15 | 0.486 | 0.808 |
RPS6KA3 | P51812 | ribosomal protein S6 kinase A3 | Kinase | 1.00 | 0.491 | 0.846 |
IDUA | P35475 | alpha-L-iduronidase | Enzyme | 3.8E-13 | 0.499 | 0.846 |
GBA | P04062 | glucosylceramidase beta | 1.4E-06 | 0.500 | 0.808 | |
SATB2 | Q9UPW6 | SATB homeobox 2 | Transcription factor | 1.00 | 0.503 | 0.769 |
SMC1A | Q14683 | structural maintenance of chromosomes 1A | 1.00 | 0.509 | 0.808 | |
SCN8A | Q9UQD0 | sodium voltage-gated channel alpha subunit 8 | Ion channel | 1.00 | 0.510 | 0.731 |
LRRK2 | Q5S007 | leucine rich repeat kinase 2 | Kinase | 2.6E-30 | 0.510 | 0.808 |
HDAC8 | Q9BY41 | histone deacetylase 8 | Epigenetic regulator | 0.98 | 0.511 | 0.885 |
GCH1 | P30793 | GTP cyclohydrolase 1 | Enzyme | 0.90 | 0.511 | 0.846 |