Disease: Generalized seizures
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CDKL5 O76039 cyclin dependent kinase like 5 Kinase 1.00 0.522 0.692
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
BCHE P06276 butyrylcholinesterase 1.1E-13 0.447 0.923
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808
EZR P15311 ezrin Cellular structure 0.18 0.476 0.808
DRD1 P21728 dopamine receptor D1 G-protein coupled receptor 0.96 0.529 0.808
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CLIP1 P30622 CAP-Gly domain containing linker protein 1 Cellular structure 0.68 0.617 0.654
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692
SCN1A P35498 sodium voltage-gated channel alpha subunit 1 Ion channel 1.00 0.477 0.808
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
ASPA P45381 aspartoacylase 4.1E-04 0.564 0.731
SARS1 P49591 seryl-tRNA synthetase 1 Enzyme 1.00 0.558 0.769
HNMT P50135 histamine N-methyltransferase 2.0E-02 0.579 0.808
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
NDST1 P52848 N-deacetylase and N-sulfotransferase 1 1.00 0.608 0.692
FOXG1 P55316 forkhead box G1 0.94 0.522 0.692
PRSS12 P56730 serine protease 12 Enzyme 8.4E-29 0.682 0.308
CRADD P78560 CASP2 and RIPK1 domain containing adaptor with death domain 0.88 0.619 0.500
NSUN2 Q08J23 NOP2/Sun RNA methyltransferase 2 Enzyme 2.6E-04 0.559 0.846
ST3GAL3 Q11203 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 2.6E-03 0.606 0.654
AIMP1 Q12904 aminoacyl tRNA synthetase complex interacting multifunctional protein 1 Enzyme 3.0E-07 0.566 0.769