Disease: Intellectual Disability
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AARS1 P49588 alanyl-tRNA synthetase 1 Nucleic acid binding 1.8E-08 0.647 0.462
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
AKT3 Q9Y243 AKT serine/threonine kinase 3 Kinase 1.00 0.512 0.808
ALG13 Q9NP73 ALG13 UDP-N-acetylglucosaminyltransferase subunit 1.00 0.631 0.577
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
ARX Q96QS3 aristaless related homeobox 0.91 0.516 0.654
ATP6 P00846 ATP synthase F0 subunit 6 Transporter 0.541 0.731
BRWD3 Q6RI45 bromodomain and WD repeat domain containing 3 1.00 0.716 0.538
CACNA2D1 P54289 calcium voltage-gated channel auxiliary subunit alpha2delta 1 Ion channel 1.00 0.641 0.500
CASK O14936 calcium/calmodulin dependent serine protein kinase Kinase 1.00 0.538 0.808
CDKL5 O76039 cyclin dependent kinase like 5 Kinase 1.00 0.522 0.692
CHD2 O14647 chromodomain helicase DNA binding protein 2 1.00 0.585 0.577
CLCN4 P51793 chloride voltage-gated channel 4 Ion channel 1.00 0.587 0.654
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
DCX O43602 doublecortin 0.30 0.511 0.769
DLG3 Q92796 discs large MAGUK scaffold protein 3 1.00 0.544 0.615
DNM1 Q05193 dynamin 1 Enzyme modulator 1.00 0.595 0.692
DNMT3A Q9Y6K1 DNA methyltransferase 3 alpha 7.4E-39 0.445 0.846
DPYS Q14117 dihydropyrimidinase Enzyme 2.8E-11 0.621 0.577
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
FGF12 P61328 fibroblast growth factor 12 Signaling 0.62 0.619 0.615
FLNA P21333 filamin A 1.00 0.419 0.846
FOXG1 P55316 forkhead box G1 0.94 0.522 0.692
GABRA1 P14867 gamma-aminobutyric acid type A receptor subunit alpha1 Ion channel 0.91 0.563 0.577
GABRB2 P47870 gamma-aminobutyric acid type A receptor subunit beta2 Ion channel 0.85 0.619 0.500