Disease: Hereditary Autosomal Dominant Spastic Paraplegia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ALDH18A1 P54886 aldehyde dehydrogenase 18 family member A1 Enzyme 8.1E-04 0.551 0.769
HSPD1 P10809 heat shock protein family D (Hsp60) member 1 0.99 0.432 0.808
KIF1A Q12756 kinesin family member 1A Cellular structure 1.00 0.559 0.692
KIF5A Q12840 kinesin family member 5A Cellular structure 1.00 0.593 0.731
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846
REEP1 Q9H902 receptor accessory protein 1 Transporter 0.99 0.653 0.423
SPAST Q9UBP0 spastin Cellular structure 1.00 0.579 0.577
SPG7 Q9UQ90 SPG7 matrix AAA peptidase subunit, paraplegin Enzyme 2.0E-36 0.436 0.885
TECPR2 O15040 tectonin beta-propeller repeat containing 2 0.58 0.663 0.423