Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
SPG16 spastic paraplegia 16 (complicated, X-linked recessive) 0.722 0.423
BIVM-ERCC5 BIVM-ERCC5 readthrough 1.3E-15 0.736 0.308
SPG14 spastic paraplegia 14 (autosomal recessive) 0.890 0.192
SPG24 spastic paraplegia 24 (autosomal recessive) 0.931 0.077
AP4M1 O00189 adaptor related protein complex 4 subunit mu 1 Extracellular structure 4.5E-17 0.638 0.500
PDHX O00330 pyruvate dehydrogenase complex component X Enzyme 9.7E-05 0.595 0.692
SLC33A1 O00400 solute carrier family 33 member 1 Transporter 9.9E-05 0.529 0.769
DNM1L O00429 dynamin 1 like Enzyme modulator 5.7E-04 0.475 0.808
KRIT1 O00522 KRIT1 ankyrin repeat containing 6.9E-04 0.500 0.808
CDK2AP1 O14519 cyclin dependent kinase 2 associated protein 1 Enzyme modulator 0.45 0.656 0.538
HSD17B6 O14756 hydroxysteroid 17-beta dehydrogenase 6 Enzyme 0.35 0.592 0.692
TECPR2 O15040 tectonin beta-propeller repeat containing 2 0.58 0.663 0.423
AP5Z1 O43299 adaptor related protein complex 5 subunit zeta 1 7.3E-31 0.700 0.346
GRID2 O43424 glutamate ionotropic receptor delta type subunit 2 Ion channel 1.00 0.670 0.500
KLF4 O43474 Kruppel like factor 4 Nucleic acid binding 1.00 0.449 0.769
KIF1C O43896 kinesin family member 1C Cellular structure 0.72 0.700 0.500
OPA1 O60313 OPA1 mitochondrial dynamin like GTPase Enzyme modulator 0.99 0.510 0.846
KIF1B O60333 kinesin family member 1B Cellular structure 1.00 0.516 0.808
RTN2 O75298 reticulon 2 0.42 0.711 0.385
CYP7B1 O75881 cytochrome P450 family 7 subfamily B member 1 Enzyme 3.3E-06 0.563 0.692
DDHD2 O94830 DDHD domain containing 2 Enzyme 1.4E-10 0.695 0.577
ERLIN2 O94905 ER lipid raft associated 2 6.7E-04 0.647 0.500
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846
ABCC6 O95255 ATP binding cassette subfamily C member 6 Transporter 5.6E-35 0.540 0.654
FARS2 O95363 phenylalanyl-tRNA synthetase 2, mitochondrial Enzyme 9.3E-09 0.615 0.731