Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
SPG16 spastic paraplegia 16 (complicated, X-linked recessive) 0.722 0.423
SPG14 spastic paraplegia 14 (autosomal recessive) 0.890 0.192
SPG24 spastic paraplegia 24 (autosomal recessive) 0.931 0.077
SPG11 Q96JI7 SPG11 vesicle trafficking associated, spatacsin 1.6E-39 0.576 0.538
SPG7 Q9UQ90 SPG7 matrix AAA peptidase subunit, paraplegin Enzyme 2.0E-36 0.436 0.885
ABCC6 O95255 ATP binding cassette subfamily C member 6 Transporter 5.6E-35 0.540 0.654
AP5Z1 O43299 adaptor related protein complex 5 subunit zeta 1 7.3E-31 0.700 0.346
TMEM67 Q5HYA8 transmembrane protein 67 2.1E-24 0.512 0.769
IFT122 Q9HBG6 intraflagellar transport 122 2.4E-24 0.560 0.846
SACS Q9NZJ4 sacsin molecular chaperone 1.1E-23 0.606 0.654
ZFYVE26 Q68DK2 zinc finger FYVE-type containing 26 4.7E-23 0.636 0.615
LAMB1 P07942 laminin subunit beta 1 Enzyme modulator 5.1E-22 0.615 0.654
EPB41L4A Q9HCS5 erythrocyte membrane protein band 4.1 like 4A 3.5E-21 0.890 0.231
GBA2 Q9HCG7 glucosylceramidase beta 2 2.0E-20 0.636 0.654
CAPN3 P20807 calpain 3 Enzyme 3.6E-19 0.564 0.615
WASHC5 Q12768 WASH complex subunit 5 Transporter 8.3E-18 0.572 0.615
AP4M1 O00189 adaptor related protein complex 4 subunit mu 1 Extracellular structure 4.5E-17 0.638 0.500
TOE1 Q96GM8 target of EGR1, exonuclease Nucleic acid binding 6.0E-16 0.682 0.462
BIVM-ERCC5 BIVM-ERCC5 readthrough 1.3E-15 0.736 0.308
CAMKMT Q7Z624 calmodulin-lysine N-methyltransferase 1.4E-15 0.510 0.808
GALC P54803 galactosylceramidase 5.2E-15 0.604 0.615
PNPLA6 Q8IY17 patatin like phospholipase domain containing 6 Enzyme 1.9E-13 0.533 0.769
ERCC5 P28715 ERCC excision repair 5, endonuclease 2.7E-13 0.499 0.731
GBE1 Q04446 1,4-alpha-glucan branching enzyme 1 Enzyme 1.1E-12 0.612 0.654
ALS2 Q96Q42 alsin Rho guanine nucleotide exchange factor ALS2 8.7E-12 0.647 0.423