Disease: Spastic Paraplegia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
KY Q8NBH2 kyphoscoliosis peptidase 1.5E-10 0.736 0.231
REEP2 Q9BRK0 receptor accessory protein 2 Transporter 0.44 0.792 0.269
ZFYVE27 Q5T4F4 zinc finger FYVE-type containing 27 1.1E-09 0.805 0.308
AP5Z1 O43299 adaptor related protein complex 5 subunit zeta 1 7.3E-31 0.700 0.346
RTN2 O75298 reticulon 2 0.42 0.711 0.385
AP4S1 Q9Y587 adaptor related protein complex 4 subunit sigma 1 Transporter 1.7E-06 0.674 0.385
AP4E1 Q9UPM8 adaptor related protein complex 4 subunit epsilon 1 Receptor 2.8E-03 0.656 0.385
TECPR2 O15040 tectonin beta-propeller repeat containing 2 0.58 0.663 0.423
ALS2 Q96Q42 alsin Rho guanine nucleotide exchange factor ALS2 8.7E-12 0.647 0.423
SPG16 spastic paraplegia 16 (complicated, X-linked recessive) 0.722 0.423
REEP1 Q9H902 receptor accessory protein 1 Transporter 0.99 0.653 0.423
DDHD1 Q8NEL9 DDHD domain containing 1 Enzyme 0.90 0.716 0.423
IBA57 Q5T440 iron-sulfur cluster assembly factor IBA57 8.4E-03 0.666 0.423
DSTYK Q6XUX3 dual serine/threonine and tyrosine protein kinase Kinase 0.51 0.700 0.462
UBQLN2 Q9UHD9 ubiquilin 2 0.85 0.656 0.462
CYP2U1 Q7Z449 cytochrome P450 family 2 subfamily U member 1 1.4E-03 0.722 0.462
NIPA1 Q7RTP0 NIPA magnesium transporter 1 Transporter 5.9E-03 0.682 0.462
AP4M1 O00189 adaptor related protein complex 4 subunit mu 1 Extracellular structure 4.5E-17 0.638 0.500
KIF1C O43896 kinesin family member 1C Cellular structure 0.72 0.700 0.500
ERLIN2 O94905 ER lipid raft associated 2 6.7E-04 0.647 0.500
UBAP1 Q9NZ09 ubiquitin associated protein 1 0.91 0.716 0.500
SPG21 Q9NZD8 SPG21 abhydrolase domain containing, maspardin 6.6E-04 0.695 0.500
SPG11 Q96JI7 SPG11 vesicle trafficking associated, spatacsin 1.6E-39 0.576 0.538
SPAST Q9UBP0 spastin Cellular structure 1.00 0.579 0.577
ARL6IP1 Q15041 ADP ribosylation factor like GTPase 6 interacting protein 1 2.2E-02 0.653 0.577