Disease: Pancytopenia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TERC telomerase RNA component 0.471 0.846
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846
TNFSF11 O14788 TNF superfamily member 11 Signaling 4.9E-03 0.453 0.846
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
DKC1 O60832 dyskerin pseudouridine synthase 1 Nucleic acid binding 1.00 0.547 0.769
SH2D1A O60880 SH2 domain containing 1A 0.39 0.525 0.731
SF3B1 O75533 splicing factor 3b subunit 1 Nucleic acid binding 1.00 0.511 0.731
RNASEH2A O75792 ribonuclease H2 subunit A Enzyme 4.2E-03 0.592 0.692
PARN O95453 poly(A)-specific ribonuclease Nucleic acid binding 3.7E-04 0.575 0.769
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923
ADA P00813 adenosine deaminase Enzyme 2.9E-12 0.440 0.885
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
GPI P06744 glucose-6-phosphate isomerase Enzyme 2.8E-06 0.491 0.769
PTPRC P08575 protein tyrosine phosphatase receptor type C Enzyme 1.00 0.435 0.808
BCR P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 0.99 0.431 0.885
PRF1 P14222 perforin 1 5.5E-06 0.540 0.692
GLB1 P16278 galactosidase beta 1 Enzyme 7.9E-10 0.448 0.808
MMUT P22033 methylmalonyl-CoA mutase Enzyme 1.7E-22 0.534 0.731
IDS P22304 iduronate 2-sulfatase 0.95 0.559 0.769