Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
LMNA P02545 lamin A/C 1.00 0.384 0.885
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846