Disease: Neurodegenerative Disorders
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PSMC1 P62191 proteasome 26S subunit, ATPase 1 Enzyme 1.00 0.780 0.462
SV2A Q7L0J3 synaptic vesicle glycoprotein 2A Transporter 0.23 0.722 0.269
QARS1 P47897 glutaminyl-tRNA synthetase 1 Enzyme 2.7E-13 0.716 0.231
GJD2 Q9UKL4 gap junction protein delta 2 Cell-cell junction 0.20 0.705 0.500
NPAS4 Q8IUM7 neuronal PAS domain protein 4 Transcription factor 0.97 0.695 0.500
SLC30A3 Q99726 solute carrier family 30 member 3 Transporter 0.54 0.691 0.423
TMED9 Q9BVK6 transmembrane p24 trafficking protein 9 Transporter 6.0E-03 0.666 0.538
OGDH Q02218 oxoglutarate dehydrogenase 1.00 0.653 0.538
GRIN2D O15399 glutamate ionotropic receptor NMDA type subunit 2D Ion channel 1.00 0.650 0.538
KCNB1 Q14721 potassium voltage-gated channel subfamily B member 1 Ion channel 1.00 0.650 0.462
ATXN10 Q9UBB4 ataxin 10 3.5E-04 0.650 0.385
NARS2 Q96I59 asparaginyl-tRNA synthetase 2, mitochondrial Enzyme 7.1E-08 0.650 0.577
PARS2 Q7L3T8 prolyl-tRNA synthetase 2, mitochondrial Enzyme 4.1E-03 0.644 0.423
HRES1 P13985 HTLV-1 related endogenous sequence 0.636 0.615
SERPINI1 Q99574 serpin family I member 1 Enzyme modulator 2.7E-02 0.631 0.462
PPP1R1B Q9UD71 protein phosphatase 1 regulatory inhibitor subunit 1B Enzyme modulator 0.24 0.617 0.500
CASP6 P55212 caspase 6 Enzyme 1.3E-04 0.610 0.615
PPP2CA P67775 protein phosphatase 2 catalytic subunit alpha 0.99 0.608 0.769
SLC18A3 Q16572 solute carrier family 18 member A3 Transporter 0.45 0.608 0.654
EPM2A O95278 EPM2A glucan phosphatase, laforin 8.7E-06 0.608 0.577
MAPK10 P53779 mitogen-activated protein kinase 10 Kinase 0.28 0.606 0.692
GALC P54803 galactosylceramidase 5.2E-15 0.604 0.615
P2RX6 O15547 purinergic receptor P2X 6 Ion channel 4.5E-09 0.599 0.769
DLG4 P78352 discs large MAGUK scaffold protein 4 Receptor 1.00 0.595 0.654
DIO2 Q92813 iodothyronine deiodinase 2 0.62 0.590 0.731